PT-141 (5mg) For Sale
PT-141, known generically as bremelanotide, is a synthetic heptapeptide melanocortin receptor agonist derived from α-melanocyte-stimulating hormone. PT-141 primarily targets central melanocortin receptors (MC1R, MC3R, and MC4R), with highest affinity for MC4R in hypothalamic regions linked to sexual behavior.
PT-141 Peptide Description
PT-141 (bremelanotide) is a synthetic peptide analogue of alpha-melanocyte-stimulating hormone (α-MSH) that acts on melanocortin receptors, particularly MC3R and MC4R, in the central nervous system. PT-141 operates via a unique mechanism distinct from peripheral-acting agents like phosphodiesterase type 5 (PDE5) inhibitors. This action is believed to stimulate sexual arousal and desire by activating neurons in the hypothalamus, a key area involved in sexual function.
Peptide Information
| Property | Value |
|---|---|
| Peptide Sequence | Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH |
| Molecular Formula | C50H68N14O10 |
| Molecular Weight | 1025.2 g/mol |
| CAS Number | 189691-06-3 |
| PubChem CID | 9941379 |
| Synonyms | Bremelanotide, 189691-06-3, PT-141, UNII-6Y24O4F92S, Bremelanotida |
Lyophilized Peptides:
These peptides are freeze-dried, a process that not only extends shelf life but also preserves the purity and integrity of the peptides during storage. We do not use any fillers in this process.
PT-141 Research
PT-141 has been investigated for its potential therapeutic effects in treating sexual dysfunction in both men and women. It acts primarily on the central nervous system, particularly targeting melanocortin receptors MC3R and MC4R, which are involved in sexual arousal and desire.
Research explores its dual application in treating hypoactive sexual desire disorder (HSDD) in women and erectile dysfunction in men, with studies showing improved sexual desire, arousal, and orgasmic function.
PT-141 and Male Sexual Dysfunction
Clinical studies have demonstrated that PT-141 can induce a significant erectile response in both healthy males and those with mild-to-moderate ED. The response is dose-dependent and the onset of action is rapid, with erections occurring approximately 30 minutes post-administration.1
PT-141 has also shown efficacy in patients who do not respond adequately to phosphodiesterase type 5 inhibitors like Viagra, suggesting it may be a viable alternative or adjunctive therapy.2
PT-141 and Female Sexual Dysfunction
Female sexual dysfunction (FSD) is a prevalent issue affecting approximately 30% of women in North America and Europe, with complex etiologies involving interpersonal, personal, and physiological factors.
Studies have shown that PT-141 selectively stimulates solicitational behaviors in female rats, which are analogous to sexual arousal in humans, without affecting other sexual behaviors such as lordosis or pacing. This indicates a specific effect on appetitive sexual behavior, suggesting its potential use in treating female sexual arousal disorders.3
Preliminary clinical data also support its role in promoting sexual desire and libido in women.4
Neurogenic Effects
Unlike PDE5 inhibitors, which augment genital blood flow via nitric oxide signaling, PT-141’s primary effects are neurogenic. By increasing dopaminergic tone in limbic circuits, it elevates sexual desire and reduces inhibitory signals from serotoninergic systems.5
Certificate of Analysis (COA) for Every Batch
A Certificate of Analysis (COA) is a document that verifies a compound’s identity, purity, and batch quality through independent laboratory testing. Every compound from BioLongevity Labs ships with a COA tied to its specific batch, so researchers can confirm exactly what they received before it enters a protocol.
Each COA reports results from third-party laboratory analysis, including:
- High-performance liquid chromatography (HPLC) for purity, typically confirmed at 99% or higher
- Liquid chromatography mass spectrometry (LC-MS) for molecular identity and mass confirmation
- Sterility and endotoxin screening where applicable
- Chemical contaminant and residual solvent checks
COAs are sourced from independent certified labs rather than in-house testing alone, giving researchers a verifiable record of molecular integrity for each batch. All compounds are supplied for research use only.

































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